Nervous System Chapter 12 I. Functions II. Organization A. Central nervous system (CNS) B. Peripheral nervous system (PNS) 1. Afferent (sensory) division a. somatic b. visceral afferent fibers 2. Efferent (motor) division a. Somatic nervous system b. Autonomic nervous system 1) Enteric nervous system III. Cells A. Neurons 1. cell body 2. processes a. dendrites b. axon 1) nerve fiber 2) axon hillock 3) telodendrion, terminal branches IV. Pathway Overview A. Sensation (afferent) neuron 1. action potential B. Integration or Association Neurons a. cerebral cortex C. Response neurons V. Neuroglia = glial cells A.Astrocytes B. Microglia C. Ependymal cells 1. blood brain barrier (bbb) D. Oligodendrocytes 1. myelin sheaths E. Satellite cells F. Schwann cells a. Nodes of Ranvier b. myelin a) white matter - tract - nerve b) grey matter - nucleus - ganglion VI. Neurophysiology A. Resting membrane potential 1. Polarized 2. Membrane potential = Volt a. resting potential B. The Impulse or Signal Initiation a. Depolarization b. Repolarization C. Refractory period D. Impulse Transmission / Propagation 1. wave of depolarization 2. wave of repolarization 3. action potential E. Continuous conduction F. Saltatory conduction a. nodes of Ranvier VII. Properties A. Threshold B. Accommodation VIII. Classification of Neurons A. Structural 1. Multipolar 2. Bipolar 3. Unipolar 1) distal process 2) central process B. Functional 1. Sensory (afferent) neurons 2. Motor (efferent) neurons 3. Interneurons (association) neurons IX. Synapse A. Synaptic cleft B. Presynaptic neuron C. Synaptic knob D. Postsynaptic neuron E. Functioning F. Notes: 1. One-way 2. Chemical `attack' point X. Classification of Neurotransmitters A. Structure 1. Acetylcholine 2. Biogenic amines 3. Amino acids 4. Peptides = neuropeptides 5. Novel Messengers B. Function 1. Effects a. Excitatory b. Inhibitory 2. Mechanism of Action a. Direct b. Indirect 1) second messenger