Krebs cycle

1. Notes
   1. Sir Hans Krebs
   2. Functions
      1. amphibolic
2. Reactions
   1. Step 1
      1. Rxn
      2. Enzyme
      3. DG°' = -7.5 kcal/mol
   2. Step 2
      1. Rxn
      2. Enzyme
         1. rxn 2a
            1. DG°' = +2 kcal/mol
         2. rxn 2b
            1. DG°' = -0.5 kcal/mol
   3. Step 3
      1. Rxn
      2. Enzyme
      3. DG°' = -2.0 kcal/mol
   4. Step 4
      1. Rxn
      2. Enzyme
      3. DG°" = -7.2 kcal/mol
   5. Step 5
      1. Rxn
         1. substrate-level phosphorylation
      2. Enzyme
         1. (a2b2) - quaternary structure
      3. DG°' = -0.8 kcal/mol
      4. Notes:
         1. nucleoside diphosphokinase
   6. Step 6
      1. Rxn
      2. Enzyme
      3. DG°' = 0
   7. Step 7
      1. Rxn
      2. Enzyme
      3. DG°' = -0.9 kcal/mol
   8. Step 8
      1. Rxn
      2. Enzyme
      3. DG°' = +7.1 kcal/molOverview / Review
   9. Equation
   10. Enter & Exits
   11. Energy Totals
       1. TCA cycle
       2. Hub rxn
       3. Glycolysis
       4. Totals