Cells and Tissues of the Immune System Chapter 2

1. Cells of the Immune System
   1. Background Info
      1. non-leukocytes
      2. leukocytes
   2. Granulocytes
      1. Mast cells
      2. Basophils
      3. Eosinophils
      4. Neutrophils
   3. Agranulocytes
      1. Monocyte
      2. Macrophage
         1. giant cells
      3. Dendritic cells
   4. Lymphoid lineage
      1. Natural killer cells
      2. Lymphocytes
         1. Ag receptors
            1. naive
            2. effector
      3. T lymphocytes
         1. thymus
         2. TCRs
         3. CD
         1. helper T cells - CD4⁺
         2. cytotoxic T cells - CD8⁺ - CTL
         3. regulatory T cells
         4. other T cells
      4. B lymphocytes
      5. plasma cell
      1. plasmablasts
      2. Tissues & Organs of the Immune System
   1. Background
      1. generative = 1°
      2. peripheral = 2°
   2. Bone marrow
      1. hematopoiesis
      2. hematopoietic stem cells
   3. Thymus
      1. anatomy
         1. cortex
            1. thymic cortical epithelial cells
         2. medulla
            1. medullary thymic epithelial cells
      2. disease
   4. Lymph Nodes
      1. vessels
         1. lymph
      2. nodes
         1. capsule
         2. subcapsular sinus
         3. cortex
            1. follicles
               1. primary follicles
               2. secondary follicles
               • germinal centers
            2. T cell zone
         4. medulla
         5. medullary sinus
      3. swollen
   5. Spleen
      1. function
      2. structure
         1. red pulp
         2. white pulp
      3. homeostatic imbalance
   6. Cutaneous & mucosal immune system
      1. MALT
   7. Tonsils
      1. structure
   8. Peyer's patches
   9. Appendix