Transcription Chapter 7A
  1. Nucleic Acids
    1. Differences
    2. Gene
      1. coding region
    3. Transcription
    4. Template
    5. RNA structure
      1. hairpins
      2. stem-loop
  2. Process Overview
    1. Transcript
      1. +1
      2. downstream
      3. upstream
    2. Error rate
  3. Types of RNA
  4. Transcription and Gene Structure
    1. General transcription
      1. initiation
        1. transcription bubble
      2. strand elongation
        1. pyrophosphate
        2. stable
      3. termination
    2. Amplification
    3. Prokaryotic transcription
      1. RNA polymerase
        1. sigma factor
      2. promoter
      3. operon
      4. terminator
    4. Eukaryotic transcription
      1. promoter
      2. RNA polymerases
      3. enhancers
      4. general transcription factors
        1. TFIID
        2. TFIIH
  5. RNA Processing
    1. Prokaryotic
      1. polycistronic
    2. Eukaryotic
      1. monocistronic
      2. RNA cap
        1. process
      3. polyadenylation
        1. poly(A) polymerase
        2. poly(A) tail
      4. splicing
        1. introns & exons
        2. spliceosome
          1. snRNAs
          2. snRNPs
        3. process
          1. lariat structure
        4. alternative splicing
      5. export
        1. export proteins
  6. RNA degradation
    1. Half life
    2. Pathways of mRNA degradation
    3. Additional control
      1. miRNAs
      2. siRNAs
      3. half life control