Antimicrobial Treatment Chapter 10

1. Vocabulary
   1. Prophylaxis
   2. Antimicrobial Chemotherapy
   3. Antimicrobials
   4. Antibiotics
   5. Semisynthetic
   6. Synthetic
   7. Narrow-Spectrum
   8. Broad-Spectrum
2. Antimicrobial Considerations
3. History
   1. Salvarsan
   2. Sulfonamides
   3. Penicillin
   4. Now others
4. Diagnosis
5. Discovery & Susceptibility
   1. Evaluation
   2. Use-dilution test
   3. Tube-dilution test
   4. Kirby-Bauer
      1. zone if inhibition
6. Antimicrobial classes
   1. Target = Cell wall
      1. Penicillins
      2. Cephalosporins
      3. Vancomycin
   2. Target - Protein synthesis
      1. Aminoglycosides
      2. Tetracycline
      3. Macrolides
   3. Target - folic acid synthesis
      1. Sulfonamides
   4. Target - DNA
      1. Fluoroquinolones
7. Anti-fungals
8. Anti-protozoals
   1. Metronidazole
9. Anti-virals
   1. Strategies
10. Antimicrobial Resistance
    1. Intrinsic
    2. Acquisition
    3. Mechanisms