Pituitary & Thyroid

1. Anatomy
   1. Hypothalamus
      1. master endocrine gland
   2. Pituitary gland
      1. anatomy
         1. posterior
         2. anterior
      2. affects
2. Anterior Pituitary Hormones
   1. ACTH
      1. cosyntropin
   2. Growth hormone
      1. IGFs
      2. somatropin
      3. somatostatin (GHIH)
         1. octreotide
         2. lanreotide
   3. Gonadotropins
      1. GnRH
         1. lruprolide
         2. goserelin
         3. nafarelin
         4. histrelin
      2. gonadotropins
      3. FSH
      4. LH)
      5. drugs
         1. menotropins
         2. urofollitropin
         3. follitropin
         4. choriogonadotropin
   4. Prolactin
3. Posterior Pituitary Hormones
   1. Oxytocin
   2. Vasopressin = ADH
      1. drug
         1. desmopressin
4. Thyroid
   1. Gland
   2. Hormone production
      1. Thyrotropin Releasing Hormone (TRH)
      2. Thyroid Stimulating Hormone (TSH)
         1. aka thyrotropin & thyrotropic hormone
            1. iodine trapping
            2. iodination of thyroglobulin
            3. condensation
            4. proteolysis
         2. T4 = thyroxine
         3. T3 = triiodothyronine
   3. Hormone circulation
      1. thyroxine-binding globulin (TBP)
   4. Physiological actions
      1. caloric effect
   5. Hypothyroidism
      1. levothyroxine - Synthroid = T4
      2. liothyronine - Cytomel = T3
      3. liotrix - Thyrolar = T4/T3
   6. Hyperthyroidism = thyrotoxicosis
      1. Graves disease
      2. removal of thyroid
      3. inhibition of hormone synthesis
         1. propylthiouracil - (PTU)
         2. methimazole - Tapazole
      4. block hormone release
         1. thyroid storm